Elyon Biologics

Semaglutide is a 34-amino acid GLP-1 receptor agonist with a C18 fatty diacid chain enabling albumin binding for a ~7-day half-life. It potently stimulates glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite via central hypothalamic pathways. Used extensively in metabolic research, obesity biology, and pancreatic beta-cell function studies.

Tirzepatide is a 39-amino acid dual GIP/GLP-1 receptor co-agonist. It incorporates a C20 fatty diacid moiety conferring albumin binding and an ~5-day half-life. Research demonstrates synergistic incretin effects: superior insulin secretion stimulation, appetite suppression, energy expenditure modulation, and adipose tissue remodeling compared to selective GLP-1 agonism alone.

Retatrutide is an investigational triple agonist acting at GLP-1, GIP, and glucagon receptors. The glucagon receptor activity adds direct hepatic lipid oxidation and thermogenic energy expenditure to the incretin effects of dual agonism. Preclinical and early clinical research shows exceptional efficacy in metabolic rate modulation and body composition studies.

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide (GEPPPGKPADDAGLV) isolated from human gastric juice. It is a potent promoter of angiogenesis (upregulating VEGFR2, EGF, and FAK-paxillin signaling), accelerates tendon-to-bone healing, exhibits gastroprotective effects via NO-system modulation, and protects against NSAID-induced gut damage in research models.

TB-500 is a synthetic analogue of the active region of Thymosin Beta-4 (Tβ4), the most abundant intracellular actin-sequestering protein. It binds G-actin, promoting cell migration, angiogenesis, and tissue repair. Research demonstrates acceleration of wound healing, reduced inflammation via NF-κB downregulation, and cardioprotective effects in ischemia-reperfusion models.

Wolverine is a proprietary research blend combining BPC-157 and TB-500 in a single formulation. The combination targets complementary tissue repair pathways: BPC-157 drives angiogenesis and NO-mediated healing while TB-500 promotes actin-mediated cell migration and anti-inflammatory signaling. Used in research models requiring synergistic regenerative activity.

CJC-1295 is a synthetic GHRH analogue with a C8 fatty acid via Drug Affinity Complex (DAC) technology, enabling covalent albumin binding and a plasma half-life of 6–8 days. It stimulates pulsatile GH secretion from pituitary somatotrophs and downstream IGF-1 production. Widely used in GH axis, somatotroph biology, and metabolic research protocols.

Ipamorelin is a selective pentapeptide ghrelin receptor (GHS-R1a) agonist and GH secretagogue. Unlike GHRP-2 and GHRP-6, it stimulates GH release with minimal effect on cortisol, prolactin, or ACTH, making it highly specific for GH axis research. It acts synergistically with GHRH analogues and demonstrates dose-dependent GH pulse amplification.

Tesamorelin is a synthetic analogue of endogenous GHRH(1-44) conjugated to a trans-3-hexenoic acid group, increasing stability against dipeptidyl peptidase-IV cleavage. It stimulates pituitary GH secretion and is extensively studied in models of growth hormone deficiency, visceral adiposity, lipid metabolism, and cognitive function in aging research.

GHK-Cu (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring human plasma tripeptide with high copper(II) affinity. It activates over 4,000 genes involved in tissue remodeling, wound healing, and anti-inflammatory signaling. Research demonstrates activation of collagen, elastin, and glycosaminoglycan synthesis, antioxidant enzyme upregulation, and VEGF-mediated angiogenesis.

Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of endogenous human GHRH (GHRH 1-29-NH₂), the biologically active fragment. It binds pituitary GHRH receptors and stimulates physiologic pulsatile GH secretion, preserving the natural GH feedback axis. Foundational tool for GH-axis, somatotroph function, and aging research protocols.

MOTS-c (Mitochondrial ORF of the 12S rRNA Type-C) is a 16-amino acid mitochondria-derived peptide encoded in mitochondrial DNA. It activates AMPK via the folate cycle–AICAR pathway, improves insulin sensitivity, enhances mitochondrial biogenesis, and has been shown to extend lifespan in model organisms. Active research in metabolic homeostasis, aging biology, and exercise physiology.

Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic heptapeptide analogue of tuftsin developed at the Institute of Molecular Genetics, Moscow. It modulates IL-6, BDNF, and serotonin signaling with notable anxiolytic and nootropic properties in preclinical models. Studied for stress response attenuation, memory enhancement, and neurotrophin modulation.

Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide derived from ACTH(4-10). It potently upregulates BDNF, VEGF, and NGF expression in the brain and exhibits procognitive, neuroprotective, and anti-inflammatory effects in preclinical models. Studied for attention, memory consolidation, and ischemic neuroprotection research.

NAD⁺ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme in over 500 enzymatic reactions. It serves as an electron carrier in mitochondrial oxidative phosphorylation, a substrate for sirtuins (SIRT1-7) regulating gene expression and metabolism, and for PARP enzymes in DNA repair. Research interest centers on its role in aging, neurodegeneration, mitochondrial dysfunction, and metabolic disease.

Glutathione (γ-L-glutamyl-L-cysteinyl-glycine) is the most abundant intracellular non-protein thiol and primary antioxidant. It directly scavenges reactive oxygen species, serves as a cofactor for glutathione peroxidase and S-transferases, regulates protein thiol status via glutathionylation, and participates in phase II xenobiotic detoxification. Critical in oxidative stress, redox signaling, and immune function research.

IGF-1 LR3 (Long Arg³-IGF-1) is a recombinant analogue of IGF-1 with an N-terminal 13-amino acid extension and an Arg substitution at position 3. These modifications reduce binding to IGF-binding proteins (IGFBPs) by ~1000-fold, extending half-life to ~20–30 hours vs. ~12 min for native IGF-1. It potently activates IGF-1R and IR-A, driving PI3K/Akt/mTOR and Ras/MAPK anabolic signaling.

Epithalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analogue of Epithalamin, a pineal gland extract. Research by Khavinson et al. demonstrates telomerase activation (upregulating hTERT expression), elongation of telomeres in somatic cells, antioxidant activity, melatonin synthesis regulation, and extension of lifespan in multiple model organisms. Active research in biogerontology and epigenetic aging.

Melanotan II (MT-II) is a cyclic synthetic analogue of α-MSH (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH). It is a potent, non-selective melanocortin receptor agonist with high affinity at MC1R (melanogenesis), MC3R/MC4R (appetite and energy regulation), and MC5R. Used in research on pigmentation pathways, energy homeostasis, and melanocortin receptor pharmacology in preclinical models.

A synergistic dual-peptide growth hormone secretagogue blend combining Tesamorelin (GHRH analogue) and Ipamorelin (GHS-R1a agonist). The combination drives physiologic pulsatile GH release via complementary receptor pathways — GHRH stimulation of somatotrophs and selective ghrelin receptor activation — with minimal cortisol or prolactin response.

Advanced four-peptide GH secretagogue blend targeting multiple receptor pathways simultaneously. Tesamorelin and Ipamorelin provide GHRH/GHRP axis stimulation, GHRP-2 adds additional GHS-R1a agonism with IGF-1 amplification, and PEG-MGF (PEGylated Mechano Growth Factor) drives local muscle satellite cell activation and tissue repair signaling.

GLOW is a proprietary three-peptide regenerative blend combining GHK-Cu (50 mg), BPC-157 (10 mg), and TB-500 (10 mg). GHK-Cu activates collagen and elastin synthesis and upregulates antioxidant enzymes; BPC-157 drives angiogenesis and NO-mediated cytoprotection; TB-500 promotes actin-mediated cell migration and reduces inflammation. Designed for comprehensive skin remodeling and tissue repair research.

KLOW builds on the GLOW formula by adding KPV (Lys-Pro-Val), a potent tripeptide fragment of alpha-MSH with powerful anti-inflammatory and gut-protective properties. The four-peptide combination — GHK-Cu (50 mg), BPC-157 (10 mg), TB-500 (10 mg), KPV (10 mg) — targets skin remodeling, angiogenesis, cellular migration, and NF-κB-mediated inflammatory pathway research simultaneously.

KPV (Lys-Pro-Val) is a C-terminal tripeptide fragment of alpha-MSH with potent anti-inflammatory properties. It acts directly on immune cells, downregulating NF-κB signaling and pro-inflammatory cytokines including TNF-α and IL-6. Studied for gut inflammation, wound healing, and antimicrobial activity in preclinical models.

Thymosin Beta-4 (Tβ4) is the full 43-amino acid naturally occurring endogenous peptide and the most abundant intracellular actin-sequestering protein. It regulates actin polymerization, promotes cell migration, angiogenesis, and tissue regeneration. Studied for cardiac repair, wound healing, corneal regeneration, and anti-inflammatory signaling via ILK/Akt pathway modulation.

SS-31 (Elamipretide, D-Arg-dimethylTyr-Lys-Phe-NH₂) is a cell-permeable tetrapeptide that selectively targets the inner mitochondrial membrane by binding cardiolipin. It improves electron transport chain efficiency, reduces reactive oxygen species generation, and inhibits mitochondrial permeability transition pore opening. Active research in mitochondrial dysfunction, ischemia-reperfusion injury, and aging biology.

PT-141 (Bremelanotide) is a cyclic heptapeptide analogue of alpha-MSH and a non-selective melanocortin receptor agonist with high affinity at MC3R and MC4R. Unlike Melanotan II it does not cause significant skin pigmentation. Studied for central nervous system melanocortin pathway modulation, hypothalamic signaling, and autonomic nervous system research in preclinical models.

BURN is a proprietary research blend combining Retatrutide (15mg) and Tirzepatide (5mg). It targets GLP-1R, GIPR, and GCGR simultaneously, combining dual incretin receptor activation with glucagon-mediated thermogenesis and hepatic lipid oxidation for comprehensive metabolic pathway research.

AOD-9604 is a synthetic peptide fragment of human growth hormone (hGH176-191) with a tyrosine component added. It stimulates lipolysis and inhibits lipogenesis without affecting IGF-1 levels or blood glucose. Used in adipose tissue metabolism, fat oxidation pathway, and obesity research models.

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide naturally secreted by the thymus. It modulates T-cell function, enhances NK cell activity, upregulates MHC class I expression, and stimulates dendritic cell maturation. Extensively studied in immune function, viral immunity, and immunodeficiency research.

A comprehensive immunomodulatory research blend combining Thymosin Alpha-1 (3.2mg), Thymalin (2.5mg), Ursolic Acid (5mg), and RG3 Ginsenoside (25mg). Targets multiple immune regulatory pathways including thymic peptide signaling, NF-κB inhibition, and ginsenoside-mediated immune modulation.

Thymosin Beta-4 (Tβ4) is the full-length 43-amino acid naturally occurring actin-sequestering protein. It binds G-actin, promotes cell migration, wound healing, and angiogenesis via VEGF and laminin-5 upregulation. Distinguished from TB-500 (its active fragment) by its complete sequence and broader regulatory scope.

BPC Mod is an advanced regenerative blend combining BPC-157 (10mg), Thymosin Beta-4 (2.5mg), KPV tripeptide (2mg), and PEG-MGF (1mg). Each component targets distinct repair pathways: BPC-157 for angiogenesis, TB4 for actin-mediated migration, KPV for anti-inflammatory signaling, and P-MGF for satellite cell activation.

GLOW is a regenerative research blend combining GHK-Cu (50mg), BPC-157 (10mg), and Thymosin Beta-4 (10mg). Targets complementary tissue repair: copper peptide gene activation and collagen synthesis, BPC-157 angiogenesis, and TB4 actin-mediated cell migration and anti-inflammatory activity.

KLOW extends the Glow formula by adding KPV (10mg), a C-terminal fragment of alpha-MSH with potent anti-inflammatory properties. Targets tissue repair, collagen synthesis, angiogenesis, actin remodeling, and NF-κB-mediated inflammatory pathway modulation in a single research formulation.

Delta Sleep-Inducing Peptide (DSIP) is a nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from thalamic venous blood. Studied for sleep regulation, stress response modulation, and neuroendocrine signaling. Also researched for antioxidant activity and gonadotropin-releasing hormone modulation.

KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of alpha-MSH with potent anti-inflammatory properties independent of melanocortin receptor activation. It inhibits NF-κB signaling, reduces pro-inflammatory cytokine production, and crosses the intestinal epithelium. Used in gut inflammation, wound healing, and cellular inflammatory pathway research.

The 2X Blend is a dual GH secretagogue research formulation combining either Tesamorelin (5mg) + Ipamorelin (5mg) or CJC-1295 (5mg) + Ipamorelin (5mg). These pairings synergistically amplify pulsatile GH release by combining GHRH-mediated somatotroph stimulation with ghrelin receptor agonism.

The 3X Blend combines Tesamorelin (5mg), Mechano Growth Factor (500mcg), and Ipamorelin (2.5mg). Tesamorelin drives pituitary GH release, Ipamorelin amplifies GH pulses via ghrelin receptor agonism, and MGF promotes local muscle satellite cell activation and IGF-1 splice variant signaling.

The 4X Blend is a comprehensive GH axis research formulation combining GHRP-2 (1.6mg), Ipamorelin (1.2mg), Tesamorelin (1.6mg), and PEG-MGF (1mg). Each component activates distinct GH-axis receptors and downstream signaling pathways for multi-target GH secretagogue research.

PT-141 (Bremelanotide) is a cyclic heptapeptide analogue of alpha-MSH and non-selective melanocortin receptor agonist with high affinity at MC3R and MC4R. Unlike Melanotan II it does not cause significant skin pigmentation. Studied for central nervous system melanocortin pathway modulation and hypothalamic signaling research.

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a small peptide derived from Angiotensin IV with high hepatocyte growth factor (HGF) potentiating activity. It facilitates MET receptor signaling, promotes synaptogenesis, and has demonstrated potent procognitive effects in preclinical neurodegenerative models.

Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family that signals through TrkB receptors. It promotes neuronal survival, synaptic plasticity, long-term potentiation, and adult neurogenesis. Used in neurodegeneration, depression, memory, and learning research models.

Kisspeptin-10 is a 10-amino acid peptide derived from the KISS1 gene that acts as the master regulator of GnRH pulsatile release. It activates GPR54/KISS1R receptors on hypothalamic GnRH neurons, regulating the HPG axis. Used in reproductive endocrinology, puberty, and neuroendocrine research.

Oxytocin is a cyclic nonapeptide neurohypophysial hormone produced in the hypothalamus. It modulates social behavior, pair bonding, maternal behavior, stress response, and autonomic nervous system function via OXTR receptors. Used in social neuroscience, neuroendocrinology, and stress physiology research.

SS-31 (Elamipretide) is a cell-permeable tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that selectively concentrates in the inner mitochondrial membrane via cardiolipin interaction. It reduces mitochondrial ROS, stabilizes cristae architecture, and preserves ATP synthesis. Used in mitochondrial dysfunction, ischemia-reperfusion, and aging research.

Methylcobalamin is the neurologically active form of Vitamin B-12. It serves as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase, supporting one-carbon metabolism, myelin synthesis, DNA methylation, and homocysteine regulation. Used in neurological function and methylation pathway research.

Curcumin (diferuloylmethane) is the primary bioactive polyphenol from Curcuma longa. It inhibits NF-κB, COX-2, and LOX pathways, modulates Nrf2/HO-1 antioxidant response, and downregulates pro-inflammatory cytokines. Used in oxidative stress, chronic inflammation, and cancer pathway research.

Quercetin is a ubiquitous plant flavonoid with broad bioactivity. It inhibits PI3K/Akt/mTOR signaling in senescent cells (senolytic), inhibits NLRP3 inflammasome, and exhibits antiviral, antihistamine, and antioxidant activity. Used in senescence, inflammation, and flavonoid-receptor interaction research.

Resveratrol is a stilbene polyphenol and potent SIRT1 activator. It activates AMPK, inhibits mTOR, and modulates the SIRT1/PGC-1α axis to enhance mitochondrial biogenesis. Studied in caloric restriction mimicry, longevity biology, cardiovascular protection, and NAD+/sirtuin pathway research.

Follistatin-344 is a naturally occurring glycoprotein that binds and neutralizes myostatin (GDF-8) and activin A. It suppresses follicle-stimulating hormone (FSH) and promotes muscle fiber hypertrophy. Used in muscle biology, myostatin signaling, and reproductive endocrinology research.

LL-37 is the only cathelicidin family host defense peptide expressed in humans. It exhibits broad-spectrum antimicrobial activity, modulates TLR4 and NF-κB signaling, promotes wound healing, and regulates immune cell chemotaxis. Used in innate immunity, antimicrobial peptide research, and immunomodulation studies.

5-Amino-1-methylquinolinium (5-Amino-1MQ) is a selective cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). By inhibiting NNMT it raises intracellular SAM/SAH ratios, enhances NAD+ availability, activates SIRT1, and reduces adipogenesis. Used in obesity, NAD+ metabolism, and epigenetic methylation research.

MIC (Methionine, Inositol, Choline + Alpha-GPC) is a lipotropic research formulation supporting hepatic fat metabolism. Methionine is a methyl donor in one-carbon metabolism; Inositol modulates insulin signaling; Choline is essential for phosphatidylcholine synthesis; Alpha-GPC provides bioavailable choline for acetylcholine biosynthesis.

Lipo Mino B is an IV-grade lipotropic research blend combining B vitamins, methionine, inositol, and choline in a sterile injectable formulation. Supports hepatic lipid metabolism, methylation cycling, mitochondrial energy production, and phospholipid biosynthesis pathway studies.

Advanced Topical GHK-Cu is a research-grade copper peptide formulation optimized for transdermal delivery studies. GHK-Cu activates 4,000+ genes involved in collagen, elastin, and glycosaminoglycan synthesis, VEGF-mediated angiogenesis, and antioxidant enzyme upregulation. Available in 15mL and 30mL research sizes.